For rheumatoid arthritis, up to 2. 6 g fish oil 1. 6 g EPA twice a day. For mild pain, a complement that provides 1000mg of omega3s per day could be advantageous. Hand pain, normal stiffness or redness and inflammation, are signs that more help is needed and the dosage can be increased. For severe pain, up to 3 grams of fish oil once per day can help to lessen joint irritation.