siamese fighting fish tank set upFor rheumatoid arthritis, up to 2. 6 g fish oil 1. 6 g EPA twice a day. For mild pain, a complement that provides 1000mg of omega3s per day might be advantageous. Hand pain, typical stiffness or redness and inflammation, are signs that more assistance is needed and the dosage can be greater. For severe pain, up to 3 grams of fish oil once per day can help to reduce joint inflammation.